Description

Cultrex®BasementMembraneExtract(BME)isasolubleformofbasementmembranepurifiedfromEngelbreth-Holm-Swarm(EHS)tumor.Thisextractprovidesanaturalextracellularmatrixhydrogelthatpolymerizesat37°Ctoformareconstitutedbasementmembrane.Basementmembranesarecontinuoussheetsofspecializedextracellularmatrixthatformaninterfacebetweenendothelial,epithelial,muscle,orneuronalcellsandtheiradjacentstromaandthatplayanessentialroleintissueorganizationbyinfluencingcelladhesion,migration,proliferation,anddifferentiation.ThemajorcomponentsofBMEincludelaminin,collagenIV,entactin,andheparinsulfateproteoglycans.

TheCultreCoat®24WellBMECoatedCellInvasionAssayprovidesatoolforassessingcellinvasionthroughastandardizedthickcoatingofreconstitutedbasementmembranematrixandisavailableina24wellformat.

IdentificationofanEGFRvIII-JNK2-HGF/c-Met–SignalingAxisRequiredforIntercellularCrosstalkandGlioblastomaMultiformeCellInvasion
VanessaC.Saunders,MarieLafitte,IsabelAdrados,VictorQuereda,DanielFeurstein,YuanYuanLing,MohammadFallahi,LauraH.Rosenberg,andDerekR.Duckett
Mol.Pharmacol.,Oct2015;88:962–969.
http://molpharm.aspetjournals.org/cgi/content/abstract/88/6/962

Trevigen提供多种产品来测量氧化应激和DNA损伤。我们的彗星实验®产品线是为彗星试验，其中包括试剂，试剂盒，设备和分析软件的唯一完整和优化的商用平台。我们的TACS ®（Trevigen公司凋亡的细胞系统）产品已被广泛使用，并列举多年来，研究人员对他们的无与伦比的品质认可。