Description

Cultrex®MouseColllagen IVispurifiedfromEngelbreth-Holm-Swarm(EHS)tumor.CollagenIV isacomponentofthebasementmembranewhichisacontinuoussheetofspecializedextracellularmatrixthatformsaninterfacebetweenendothelial,epithelial,muscle,orneuronalcellsandtheiradjacentstromaandthatplaysanessentialroleintissueorganizationbyinfluencingcelladhesion,migration,proliferation,anddifferentiation.

Cultrex®5XCollagenIVSolutionisapurifiedbasementmembraneproteinthathasbeendeveloped,producedandqualifiedfortheCultrex®CollagenIVCellInvasionAssays.

Qualitycontrolspecifications:

• Mousecoloniesareroutinelyscreenedforpathogensusing mouseantibodyproduction(MAP)testing.
• Engelbreth-Holm-Swarm(EHS)tumorisLDEV-free.
• Nobacterialorfungalgrowthdetectedafterincubationat37°Cfor14daysfollowingUSPsterilitytestingguidelines.
• Endotoxinconcentration≤20EU/mlbyLimulusAmoebocyteLysate(LAL)assay.
• Proteinconcentrationof0.5mg/ml.
• NomycoplasmacontaminationdetectedbyPCR.
• Providedin50mMHydrochloricAcid,1mMTCEP–HCl.
• Purity ≥90%(SDS-PAGE).
• BIOLOGicalactivitydeterminedforeachlot:
  • TestedforABIlitytopromoteattachmentandspreADIngofratPC-12pheochromocytomacells.
  • PerformancetestedinCultrex®CollagenIVCellInvasionAssay.

Trevigen提供多种产品来测量氧化应激和DNA损伤。我们的彗星实验®产品线是为彗星试验，其中包括试剂，试剂盒，设备和分析软件的唯一完整和优化的商用平台。我们的TACS ®（Trevigen公司凋亡的细胞系统）产品已被广泛使用，并列举多年来，研究人员对他们的无与伦比的品质认可。