Description

TheCultrex®InVitroAngiogenesisAssayTubeFormationKitwasdevelopedfortheevaluation ofinducersandinhibitorsofendothelialcelltubeformation. Duringthecourseoftheassay,endothelialcellsareseededonathickgelofBasementMembraneExtractinthepresenceofangiogenesismodulatingagents. Ifthemediumispermissivetotheangiogenicresponse,cellswillselfassembleintotubenetworkswithinhours;ifthereareinhibitorsinthemedium,tubenetworkformationwillbeincompleteornonexistent.Sulforaphane[1-isothiocyanato-(4R)-methylsulfinyl)-butane],foundinbroccoliandothercruciferousvegetables,isanaturallyoccurringcancerchemopreventiveagent,andisprovidedasacontrolinhibitortovisualizethisprocess. EndothelialcellsmaybefluorescentlylabeledusingCalceinAM,andimagescapturedusingamicroscopecameramaybeanalyzetoquantifytheangiogenicresponse. Cultrex^®InVitroAngiogenesisAssayKitprovidesacost-effectivemethodforinvestigationofProspectiveangiogenesisinhibitorsina96wellplateformat.

Syndecan-4IsaMajorSyndecaninPrimaryHumanEndothelialCellsInVitro,ModulatedbyInflammatoryStimuliandInvolvedinWoundHealing
TramThuVuong,TrineM.Reine,AmandaSudworth,TrondG.Jenssen,andSveinO.Kolset
JournalofHistochemistry&Cytochemistry,Feb2015;10.1369/0022155415568995
http://jhc.sagepub.com/cgi/content/abstract/0022155415568995v2

Gastrictumour-derivedANGPT2regulationbyDARPP-32promotesangiogenesis
ZhengChen,ShouminZhu,JunHong,MohammedSoutto,DunFaPeng,AbbesBelkhiri,ZekuanXu,andWaelEl-Rifai
Gut,Mar2015;10.1136/gutjnl-2014-308416.
http://gut.bmj.com/cgi/content/abstract/gutjnl-2014-308416v1

“TheRoleofAngiogenesisinthePersistenceofChemoresistancein
EpithelialOvarianCancer”
“OsamaNusrat,JimmyBelotte,NicoleM.Fletcher,IraMemaj,MohammedG.Saed,MichaelP.Diamond,
andGhassanM.Saed”
ReproductiveSciences,Nov2016;23:1484–1492
http://rsx.sagepub.com/cgi/content/abstract/23/11/1484

Trevigen提供多种产品来测量氧化应激和DNA损伤。我们的彗星实验®产品线是为彗星试验，其中包括试剂，试剂盒，设备和分析软件的唯一完整和优化的商用平台。我们的TACS ®（Trevigen公司凋亡的细胞系统）产品已被广泛使用，并列举多年来，研究人员对他们的无与伦比的品质认可。