Description

TheXTTCellProliferationAssay(XTT-CPA)isasensitivekitforthemeasurementofcellproliferation.Cleavageofthetetrazoliumsalttoformazanoccursviathesuccinate-tetrazoliumreductasesysteminthemitochondriaofmetabolicallyactivecells.

Features:

• Allowsmeasurementofcellproliferation,cellviABIlityorcytotoxicity.
• Rapiddeterminationinmicroplates(nosolubilizationstepasinanMTTassay).
• ReproducIBLeandsensitiveresults.
• NorADIoactivity.
• Idealforhighthroughputassays(nowashingorotherstepsthatcancausecelllossandvariability).

Akt-ActivatedEndotheliumConstitutestheNicheforResidualDiseaseandResistancetoBevacizumabinOvarianCancer
BellaS.Guerrouahen,JenniferPasquier,NadineAbuKaoud,MahtabMaleki,Marie-ClaudeBeauchamp,AmberYasmeen,PegahGhiabi,RaphaelLis,FabienVidal,AhmedSaleh,WalterH.Gotlieb,ShahinRafii,andArashRafii
Mol.CancerTher.,Dec2014;13:3123–3136.
http://mct.aacrjournals.org/cgi/content/abstract/13/12/3123

ASpliceVariantoftheHumanIonChannelTRPM2ModulatesNeuroblastomaTumorGrowththroughHypoxia-inducibleFactor(HIF)-1/2{alpha}
Shu-jenChen,NicholasE.Hoffman,SanthanamShanmughapriya,LeiBao,KerryKeefer,KathleenConrad,SalimMerali,YoshinoriTakahashi,ThomasAbraham,IwonaHirschler-Laszkiewicz,JuFangWang,Xue-QianZhang,JianliangSong,CarlosBarrero,YuguangShi,YukaImamuraKawasawa,MichaelBayerl,TianyuSun,MustafaBarbour,Hong-GangWang,MuniswamyMadesh,JosephY.Cheung,andBarbaraA.Miller
J.Biol.Chem.,Dec2014;289:36284–36302.
http://www.jbc.org/cgi/content/abstract/289/52/36284

“DepletionoftheHumanIonChannelTRPM2inNeuroblastoma
DemonstratesItsKeyRoleinCellSurvivalthroughModulationof
MitochondrialReactiveOxygenSpeciesandBioenergetics”
“LeiBao,Shu-jenChen,KathleenConrad,KerryKeefer,ThomasAbraham,JohnP.Lee,JuFangWang,Xue-QianZhang,IwonaHirschler-Laszkiewicz,Hong-GangWang,SinisaDovat,BrianGans,MuniswamyMadesh,JosephY.Cheung,andBarbaraA.Miller”
J.Biol.Chem.,Nov2016;291:24449–24464
http://www.jbc.org/cgi/content/abstract/291/47/24449

Trevigen提供多种产品来测量氧化应激和DNA损伤。我们的彗星实验®产品线是为彗星试验，其中包括试剂，试剂盒，设备和分析软件的唯一完整和优化的商用平台。我们的TACS ®（Trevigen公司凋亡的细胞系统）产品已被广泛使用，并列举多年来，研究人员对他们的无与伦比的品质认可。