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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Trevigen/Cultrex® Basement Membrane Matrix, Type 3/3632-001-02/1 ml, 2 x 5 ml, 5 ml
产品编号:3632-001-02
市  场 价:¥700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$35.00
品      牌: Trevigen
公      司:Trevigen, Inc
公司分类:
Trevigen/Cultrex® Basement Membrane Matrix, Type 3/3632-001-02/1 ml, 2 x 5 ml, 5 ml
商品介绍

Description

Cultrex®BasementMembraneExtract(BME)isasolubleformofbasementmembranepurifiedfromEngelbreth-Holm-Swarm(EHS)tumor.Thisextractprovidesanaturalextracellularmatrixhydrogelthatpolymerizesat37°Ctoformareconstitutedbasementmembrane.Basementmembranesarecontinuoussheetsofspecializedextracellularmatrixthatformaninterfacebetweenendothelial,epithelial,muscle,orneuronalcellsandtheiradjacentstromaandthatplayanessentialroleintissueorganizationbyinfluencingcelladhesion,migration,proliferation,anddifferentiation.ThemajorcomponentsofBMEincludelaminin,collagenIV,entactin,andheparansulfateproteoglycans.

Cultrex®BMEType3isphysiologicallyalignedwiththeinvivoenvironmentandisrecommendedforxenografts,tumorgrafts,andotherinvivoapplications.

Qualitycontrolspecifications:

  • Mousecoloniesareroutinelyscreenedforpathogensusing mouseantibodyproduction(MAP)testing.
  • Engelbreth-Holm-Swarm(EHS)tumorisLDEV-free.
  • PathClear®–testednegativebyPCRfor 17bacterialandvirusstrainstypicallyincludedinmouseantibodyproduction(MAP)testing,plus13additionalmurineinfectiousagentsincludingLDEV,foratotalof31organismsandviruses.
  • Nobacterialorfungalgrowthdetectedafterincubationat37°Cfor14daysfollowingUSPsterilitytestingguidelines.
  • Endotoxinconcentration≤8EU/mlbyLimulusAmoebocyteLysate(LAL)assay.
  • Proteinconcentrationof12–18mg/ml.
  • NomycoplasmacontaminationdetectedbyPCR.
  • ProvidedinRoswellParkMemorialInstituted(RPMI) mediumwith10µg/mlgentamycin.
  • GelstABIlitytestedforaperiodof14daysat37°C.
  • BIOLOGicalactivitydeterminedforeachlot:
    • TumorGrowthAssay–BMEType3supportsproliferationandgrowthofbreastcancercells(MCF7)embeddedinthematrixforminimumof8days.

Catalog#3632-010-02includes: 
CatalogNumberDescriptionQty
3632-005-02Cultrex®BasementMembraneExtract,Type3,PathClear®2

GeneticIdentificationofSEMA3FasanAntilymphangiogenicMetastasisSuppressorGeneinHeadandNeckSquamousCarcinoma
ColleenL.Doçi,ConstantinosM.Mikelis,MichailS.Lionakis,AlfredoA.Molinolo,andJ.SilvioGutkind
CancerRes.,Jul2015;75:2937–2948.
http://cancerres.aacrjournals.org/cgi/content/abstract/75/14/2937

品牌介绍

Trevigen提供多种产品来测量氧化应激和DNA损伤。我们的彗星实验®产品线是为彗星试验,其中包括试剂,试剂盒,设备和分析软件的唯一完整和优化的商用平台。我们的TACS ®(Trevigen公司凋亡的细胞系统)产品已被广泛使用,并列举多年来,研究人员对他们的无与伦比的品质认可。

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