Description

TheCultrex®3DCultureSpheroidCellInvasionAssayutilizesa3DCultureQualified96WellSpheroidFormationPlatealongsideaspecializedSpheroidFormationECMtodriveaggregationand/orspheroidformationofcells.Uponcompletionofspheroidformation,thespheroidisembeddedinaninvasionmatrixcomposedofbasementmembraneproteins.Thismatrixformsahydrogelnetworkonwhichinvasivecellscantravel.Invasionmodulatingagentscanbeappliedtothesystemtoevaluatetheimpactoncellresponse.Cellinvasionisvisualizedmicroscopicallyandcanbequantifiedthroughimageanalysissoftware.

Abstract2033:Acomprehensive3Dtriplecoculturemodelforevaluatingbreastcancerprogression
GabrielJ.Benton,JayGeorge,GeraldDeGray,IrinaArnaoutova,andHyndaK.Kleinman
CancerRes.,Oct2014;74:2033.
http://cancerres.aacrjournals.org/cgi/content/abstract/74/19_Supplement/2033}

EndophilinA2PromotesTNBCCellInvasionandTumorMetastasis
TomasBaldassarre,KathleenWatt,PeterTruesdell,JalnaMeens,MarkM.Schneider,SandipK.Sengupta,andAndrewW.Craig
Mol.CancerRes.,Jun2015;13:1044–1055.
http://mcr.aacrjournals.org/cgi/content/abstract/13/6/1044

Bindingof14-3-3readerproteinstophosphorylatedDNMT1facilitatesaberrantDNAmethylationandgeneexpression
Pierre-OlivierEstève,GuoqiangZhang,V.K.ChaithanyaPonnaluri,KannegantiDeepti,HangGyeongChin,NanDai,CariSagum,KarynneBlack,IvanR.Corrêa,Jr.,MarkT.Bedford,XiaodongCheng,andSriharsaPradhan
NucleicAcidsRes.,Nov2015;10.1093/nar/gkv1162.
http://nar.oxfordjournals.org/cgi/content/abstract/gkv1162v1

CXCL16signalingmediatedmacrophageeffectsontumorinvasionofpapillarythyroidcarcinoma
SunWookCho,YoungAKim,HyunJinSun,YeAnKim,Byung-ChulOh,KaHeeYi,DoJoonPark,andYoungJooPark
Endocr.Relat.Cancer,Dec2015;23:113–124.
http://erc.endocrinology-journals.org/cgi/content/abstract/23/2/113

TheoncogenictriangleofHMGA2,LIN28BandIGF2BP1antagonizestumor-suppressiveactionsofthelet-7family
BiancaBusch,NADIneBley,SimonMüller,MarkusGlaß,DannyMisiak,MarcellLederer,MartinaVetter,Hans-GeorgStrauß,ChristophThomssen,andStefanHüttelmaier
NucleicAcidsRes.,May2016;44:3845–3864.NucleicAcidsRes.,May2016;44:3845–3864.
http://nar.oxfordjournals.org/cgi/content/abstract/44/8/3845

“TumorCellInvasionCanBeBlockedbyModulatorsofCollagenFibril
AlignmentThatControlAssemblyoftheExtracellularMatrix”
“MoranGrossman,NirBen-Chetrit,AlinaZhuravlev,RanAfik,EladBassat,InnaSolomonov,YosefYarden,
andIritSagi”
CancerRes.,Jul2016;76:4249–4258.
http://cancerres.aacrjournals.org/cgi/content/abstract/76/14/4249

“RAB2AcontrolsMT1-MMPendocyticandE-cadherinpolarizedGolgitraffickingtopromoteinvasivebreastcancerprograms”
“HiroakiKajiho,YukoKajiho,EmanuelaFrittoli,StefanoConfalonieri,GiovanniBertalot,GiuseppeViale,
PierPaoloDiFiore,AmandaOldani,MassimilianoGarre,GalinaVBeznoussenko,AndreaPalamidessi,
ManuelaVecchi,PhilippeChavrier,FrankPerez,andGiorgioScita”
EMBORep.,Jul2016;17:1061–1080.
http://EMBOr.embopress.org/cgi/content/abstract/17/7/1061

TheGAS6-AXLsignalingnetworkisamesenchymal(Mes)molecularsubtype–specifictherapeutictargetforovariancancer
JaneAntony,TuanZeaTan,ZoeKelly,JeffreyLow,MaheshChoolani,ChiaraRecchi,HaniGabra,JeanPaulThiery,andRubyYun-JuHuang
Sci.Signal.,Oct2016;9:ra97
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;9/448/ra97

MultimodularbiosensorsrevealanovelplatformforactivationofGproteinsbygrowthfactorreceptors
KrishnaK.Midde,NicolasAznar,MelanieB.Laederich,GaryS.Ma,MayaT.Kunkel,AlexandraC.Newton,andPradiptaGhosh
PNAS,Feb2015;10.1073/pnas.1420140112.
http://www.pnas.org/cgi/content/abstract/1420140112v2

Trevigen提供多种产品来测量氧化应激和DNA损伤。我们的彗星实验®产品线是为彗星试验，其中包括试剂，试剂盒，设备和分析软件的唯一完整和优化的商用平台。我们的TACS ®（Trevigen公司凋亡的细胞系统）产品已被广泛使用，并列举多年来，研究人员对他们的无与伦比的品质认可。